| Show # | Air Date | Tape Date | Season | Type | Contestants | Comments |
|---|---|---|---|---|---|---|
| 5905 | 2010-04-23 | 2010-02-02 | 26 | Regular | Carl Saras, Kathy Kenny, Phil Bucska | |
| 5904 | 2010-04-22 | 2010-02-02 | 26 | Regular | Chris Staaf, Hilary Caws-Elwitt, Phil Bucska | |
| 5903 | 2010-04-21 | 2010-02-02 | 26 | Regular | Patsy Chrysson, Phil Bucska, Amy Wilson | |
| 5902 | 2010-04-20 | 2010-02-02 | 26 | Regular | Rick Reed, Amy Wilson, Ken Starnes | |
| 5901 | 2010-04-19 | 2010-02-02 | 26 | Regular | Elizabeth Richards, Ken Starnes, Ian Silverman | |
| 5898 | 2010-04-14 | 2010-01-20 | 26 | Regular | Charlotte Hotchkiss, Ian Silverman, Arthur Christy | |
| 5897 | 2010-04-13 | 2010-01-20 | 26 | Regular | Andrew Sidden, Arthur Christy, Morgan Saxby | |
| 5896 | 2010-04-12 | 2010-01-20 | 26 | Regular | Amanda Lahan, Debbie Russell, Morgan Saxby | |
| 5895 | 2010-04-09 | 2010-01-20 | 26 | Regular | Jack Aponte, Sarah Sumadi, Morgan Saxby | |
| 5894 | 2010-04-08 | 2010-01-20 | 26 | Regular | Morgan Saxby, Marv Peña, Karla Ruksys | |
| 5893 | 2010-04-07 | 2010-01-19 | 26 | Regular | Conor Collins, Karla Ruksys, Brandon Hathaway | |
| 5892 | 2010-04-06 | 2010-01-19 | 26 | Regular | Emily Bryk, David Hoskins, Brandon Hathaway | |
| 5891 | 2010-04-05 | 2010-01-19 | 26 | Regular | Nancy West, Brandon Hathaway, Laura Hughes | |
| 5890 | 2010-04-02 | 2010-01-19 | 26 | Regular | Gary Gambino, Laura Hughes, Jessica Trudeau | |
| 5889 | 2010-04-01 | 2010-01-19 | 26 | Regular | Jessica Trudeau, Ken Burke, Matt Drury | April Fool's show with cameo appearances by Will Ferrell (as his Alex Trebek character fromSaturday Night Live), Neil Patrick Harris, Jeff Probst, and Pat Sajak. |
| 5888 | 2010-03-31 | 2010-01-13 | 26 | Regular | Matt Drury, Pat Garahan, Stacy Braverman | |
| 5887 | 2010-03-30 | 2010-01-13 | 26 | Regular | Emily Cloyd, Stacy Braverman, Manny Maldonado III | |
| 5886 | 2010-03-29 | 2010-01-13 | 26 | Regular | Melissa Kowalski, Manny Maldonado III, Regina Robbins | Regina Robbins game 5. |
| 5885 | 2010-03-26 | 2010-01-13 | 26 | Regular | Huat Lim, Kerry Smith, Regina Robbins | Regina Robbins game 4. |
| 5884 | 2010-03-25 | 2010-01-13 | 26 | Regular | Sean Burns, Susan Malmo, Regina Robbins | Regina Robbins game 3. |
| 5883 | 2010-03-24 | 2010-01-12 | 26 | Regular | Derek Honoré, Tatiana Walton, Regina Robbins | Regina Robbins game 2. |
| 5882 | 2010-03-23 | 2010-01-12 | 26 | Regular | Colin McLain, Regina Robbins, Kristian Zoerhoff | Regina Robbins game 1. |
| 5881 | 2010-03-22 | 2010-01-12 | 26 | Regular | Lisa Horowitz, Jonathan Sanchez, Kristian Zoerhoff | |
| 5880 | 2010-03-19 | 2010-01-12 | 26 | Regular | Kristian Zoerhoff, Sarah Bright, Jim Banks | |
| 5878 | 2010-03-17 | 2010-01-12 | 26 | Regular | Jim Banks, Jessica Shafer, Amanda Baber | |
| 5877 | 2010-03-16 | 2009-12-16 | 26 | Regular | Amanda Baber, Jayson Johnson, Rachel Pildis | |
| 5876 | 2010-03-15 | 2009-12-16 | 26 | Regular | Nick Gorski, Rachel Pildis, Robert Knecht Schmidt | First show consolation prizes appeared in lectern score displays at the conclusion of the game. |
| 5875 | 2010-03-12 | 2009-12-16 | 26 | Regular | Sarah Rubin, Robert Knecht Schmidt, Cyd Musni | |
| 5874 | 2010-03-11 | 2009-12-16 | 26 | Regular | Ryan Stander, Leslie Sommer, Cyd Musni | |
| 5873 | 2010-03-10 | 2009-12-16 | 26 | Regular | Kyle Mathews, Cyd Musni, Vijay Balse | Vijay Balse game 5. |
| 5872 | 2010-03-09 | 2009-12-15 | 26 | Regular | Shelby Sadler, Becki Norris, Vijay Balse | Vijay Balse game 4. |
| 5871 | 2010-03-08 | 2009-12-15 | 26 | Regular | Karen Hoffman, Kirby Nelson, Vijay Balse | Vijay Balse game 3. |
| 5870 | 2010-03-05 | 2009-12-15 | 26 | Regular | Miriam Carson, Todd Aiello, Vijay Balse | Vijay Balse game 2. |
| 5869 | 2010-03-04 | 2009-12-15 | 26 | Regular | Ann Rusthoven, Vijay Balse, Jordan Brand | Vijay Balse game 1. |
| 5868 | 2010-03-03 | 2009-12-15 | 26 | Regular | Suzanne Tetreault, Jordan Brand, Jesse Achtenberg | |
| 5867 | 2010-03-02 | 2009-12-08 | 26 | Regular | Julia Brown, Jesse Achtenberg, Amy Tyszkiewicz | |
| 5866 | 2010-03-01 | 2009-12-08 | 26 | Regular | Amy Tyszkiewicz, Anne Damon, Ben Auer | |
| 5865 | 2010-02-26 | 2009-12-08 | 26 | Regular | Kori Tyler, Ashok Bhaskar, Ben Auer | |
| 5864 | 2010-02-25 | 2009-12-08 | 26 | Regular | Ben Auer, Rhonda Scarborough, Tom Toce | |
| 5863 | 2010-02-24 | 2009-12-08 | 26 | Regular | Leslie Hurd, Graham Norris, Tom Toce | |
| 5862 | 2010-02-23 | 2009-12-07 | 26 | Regular | Stewart Yeargin, Tom Toce, Ginny Bartlett | |
| 5861 | 2010-02-22 | 2009-12-07 | 26 | Regular | Matt MacGregor, Ginny Bartlett, Elizabeth Galoozis | |
| 5860 | 2010-02-19 | 2009-12-07 | 26 | Regular | Pablo Garcia, Lisa Dengate, Elizabeth Galoozis | |
| 5858 | 2010-02-17 | 2009-12-07 | 26 | Regular | Elizabeth Galoozis, Mayank Keshaviah, Jeremy Apsley | |
| 5857 | 2010-02-16 | 2009-12-07 | 26 | Regular | Christy Brown, Jeremy Apsley, Yevgeny Shrago | |
| 5856 | 2010-02-15 | 2009-12-02 | 26 | Regular | Yevgeny Shrago, Gillian Mabrey, Rebecca Dixon | |
| 5845 | 2010-01-29 | 2009-12-02 | 26 | Regular | Jordan Piel, Francie Futterman, Rebecca Dixon | |
| 5844 | 2010-01-28 | 2009-12-02 | 26 | Regular | Rebecca Dixon, Matt Perez, James Poulos | |
| 5843 | 2010-01-27 | 2009-12-02 | 26 | Regular | James Poulos, Kelly Lathrop, Anna Tschetter | |
| 5842 | 2010-01-26 | 2009-12-02 | 26 | Regular | Anna Tschetter, Rajeev Gorowara, Andrew Fechner |